Elisabeth Simonin

Dr. Elisabeth Simonin teaches microbiology for nursing students and science majors. She is amazed by the intricate interactions between the immune system and the outside world and loves to help students explore their curiosities about biology, immunity, and microbes. Her doctoral research studied what causes allergic reactions in humans (and in horses!), and her post-doctoral research studied how pollution exposure changes the immune system. In her free time, she loves to be outside and in nature — hiking, swimming, canoeing, gardening, skiing — with her family and friends. Come say "hi"!

Education

• PhD, Immunology and Infectious Diseases, from Cornell University
• BS, Biology, from Whitworth University

Courses

BIOL 123N Principles of Microbiology 

BIOL 123L Principles of Microbiology Lab

BIOL 221 Microbiology

BIOL 221L Microbiology Lab

Publications

Wagner B, Schnabel CL, Simonin EM, Holmes CM. The Immune System of Horses and Other Equids, in Encyclopedia of Immunobiology, 2nd edn. 2024. In Press. doi:10.1016/B978-0-128-24465-4.00015-6.

Simonin EM, Wagner B. IgE-binding monocytes upregulate the coagulation cascade in allergic horses. Genes & Immunity. 2023:1-9. doi.org/10.1038/s41435-023-00207-w

Simonin EM, Babasyan S, Tarsillo J, Wagner B. IgE+ plasmablasts predict the onset of clinical allergy. Front Immunol. 2023;14:1104609. doi:10.3389/fimmu.2023.1104609

Simonin EM, Babasyan S, Wagner B. Peripheral CD23hi/IgE+ plasmablasts secrete IgE and correlate with allergic disease severity. J Immunol. 2022;209(4):665-674. doi.org/10.4049/jimmunol.2101081

Guarino C, Larson EM, Babasyan S, Rollins A, Joshi LR, Laverack M, et al. Development of a quantitative COVID-19 multiplex assay and its use for serological surveillance in a low SARS-CoV-2 incidence community. PLoS ONE. 2022;17(1):e0262868. doi.org/10.1371/journal.pone.0262868

Schnabel CL, Babasyan S, Freer H, Larson (Simonin) EM, Wagner B. New mAbs facilitate quantification of secreted equine TNF-α and flow cytometric analysis in monocytes and T cells. Vet Immunol Immunopathol. 2021;110284. doi.org/10.1016/j.vetimm.2021.110284

Raza F, Babasyan S, Larson (Simonin) EM, Freer HS, Schnabel CL, Wagner B. Peripheral blood basophils are the main source for early interleukin-4 secretion upon in vitro stimulation with Culicoides allergen in allergic horses. PLoS ONE. 2021;16:e0252243. doi.org/10.1371/journal.pone.0252243

Larson (Simonin) EM, Wagner B. Viral infection and allergy – What equine immune responses can tell us about disease severity and protection. Molec Immunol. 2021;135:329–341. doi.org/10.1016/j.molimm.2021.04.013

Larson (Simonin) EM, Babasyan S, Wagner B. IgE-binding monocytes have an enhanced ability to produce IL-8 (CXCL8) in animals with naturally occurring allergy. J Immunol. 2021;206:2312-2321. doi:10.4049/jimmunol.2001354

Larson (Simonin) EM, Babasyan S, Wagner B. Phenotype and function of IgE-binding monocytes in equine Culicoides hypersensitivity. PLoS ONE. 2020;15:e0233537. doi:10.1371/journal.pone.0233537.

Oyesola OO, Duque C, Huang LC, Larson (Simonin) EM, Früh SP, Webb LM, Peng SA, Tait Wojno ED. The prostaglandin D2 receptor CRTH2 promotes IL-33-induced ILC2 accumulation in the lung. J Immunol. 2020;204(4):1001-1011. doi: 10.4049/jimmunol.1900745

Kulinski JM, Proia RL, Larson (Simonin) EM, Olivera A. S1P 4 Regulates Passive Systemic Anaphylaxis in Mice but Is Dispensable for Canonical IgE-Mediated Responses in Mast Cells. Int J Mol Sci. 2018;19(1279):1-15. doi:10.3390/ijms19051279.

Professional Affiliations

• American Academy of Allergy, Asthma and Immunology (AAAAI)
• European Academy of Allergy and Clinical Immunology (EAACI)
• American Association of Veterinary Immunologists (AAVI)